4-N-(2-bromophenyl)pyrido[4,3-d]pyrimidine-4,7-diamine - Names and Identifiers
4-N-(2-bromophenyl)pyrido[4,3-d]pyrimidine-4,7-diamine - Physico-chemical Properties
Molecular Formula | C11H9NO
|
Molar Mass | 171.2 |
Density | 1.169±0.06 g/cm3(Predicted) |
Melting Point | 205 °C |
Boling Point | 320 °C |
Flash Point | 182.5°C |
Vapor Presure | 2.95E-06mmHg at 25°C |
pKa | 8.23±0.10(Predicted) |
Storage Condition | Sealed in dry,Room Temperature |
Refractive Index | 1.611 |
4-N-(2-bromophenyl)pyrido[4,3-d]pyrimidine-4,7-diamine - Introduction
3-hydroxy-2-phenylpyriridine, also known as 3-hydroxy-2-phenylpyriridine, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: 3-hydroxy-2-phenylpyriridine is a white to light yellow crystalline solid.
-Solubility: It can be dissolved in organic solvents such as ethanol, dimethylformamide (DMF) and dichloromethane, but it is difficult to dissolve in water.
-Melting point: Its melting point is about 138-140 ° C.
Use:
3-Hydroxy-2-phenylpyridine has a wide range of applications in organic synthesis.
-Catalyst: It can be used as an intermediate of catalyst and participate in organic reactions, such as Suzuki coupling reaction, Heck reaction and Sonogashira coupling reaction.
-Drugs: Some studies have shown that 3-Hydroxy-2-phenylpyridine may have anti-cancer, anti-viral and anti-bacterial potential, but further research is needed.
Method:
3-Hydroxy-2-phenylpyridine can be prepared by the catalytic reaction of pyridine and benzaldehyde. The specific preparation method can refer to the relevant literature reports.
Safety Information:
The following safety precautions are required when using and storing 3-hydroxy-2-phenylpyriridine:
-It is recommended to wear appropriate protective equipment such as goggles, gloves and lab coats during operation.
-Avoid contact with skin and eyes, and avoid inhaling its dust or vapor.
-The operation should be carried out in a well-ventilated place to avoid prolonged contact.
-In the event of accidental exposure or ingestion, seek medical attention immediately and provide the relevant compound's safety data sheet.
Last Update:2024-04-09 19:05:49